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Amgen announces top-line results from motesanib Phase 3 trial against NSCLC Amgen , Millennium: The Takeda Oncology Firm, and Takeda Pharmaceutical Organization Small today announced top-line results from the MONET1 pivotal Stage 3 trial evaluating motesanib administered in conjunction with paclitaxel and carboplatin in 1,090 individuals with advanced non-squamous non-small cell lung tumor .